The episode: “Teenage Strangler,” ep. 514
The riff: Blubbered by Crow in a weepy sort of voice as the camera shows a despondent woman receiving some bad news.
The explanation: This is a reference to what I assume is a regular piece of dialogue from Nancy Kulp’s character Miss Jane Hathaway on “The Beverly Hillbillies.” Hathaway was the secretary for Mr. Drysdale, the neighbor and banker for the monetarily wealthy but naive Clampett family. It was often left up to her on the show to foil his greedier schemes to take advantage of their vast fortune. There’s also a chance that this voice is supposed to be that of Margaret Drysdale, the banker’s hoighty toighty spouse, but I’m not sure why she would call her own husband “Mr. Drysdale.”
Novelty factor: I honestly didn’t know–“The Beverly Hillbillies” was never a show whose reruns held much interest for me. The MST3k writers seemed to like it, though, as there are references in many other episodes that I’ve also recognized. The “Mr. Drysdale” riff is used in multiple other episodes as well, I believe.